The diffusion of water across a selectively permeable membrane
from an area of higher concentration to an area of lower concentration
is osmosis (Gr. osmos, pushing). Osmosis is just a special
type of diffusion, not a different method. The term tonicity
(Gr. tonus, tension) refers to the relative
concentration of solutes in the water inside and outside the
cell. For example, in an isotonic (Gr. isos, equal tonus, tension)
solution, the solute concentration is the same inside and
outside a red blood cell. The concentration of water
molecules is also the same inside and outside the cell. Thus,
water molecules move across the plasma membrane at the same
rate in both directions, and there is no net movement of water in
either direction.
In a hypertonic (Gr. hyper, above) solution, the solute concentration
is higher outside the red blood cell than inside. Because
the concentration of water molecules inside the cell is higher than
outside, water moves out of the cell, which shrinks.
This condition is called crenation in red blood cells.
In a hypotonic (Gr. hypo, under) solution, the solute concentration
is lower outside the red blood cell than inside. Conversely,
the concentration of water molecules is higher outside the
cell than inside. As a result, water moves into the cell, which
swells and may burst
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